What is another word for apraclonidine?

Synonyms for apraclonidine
apr·a·cloni·dine

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appurtenant, appx, appy, apr, apra, apraclonidine, apractic, apraxic, après, apricot, apricot bar

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Which of the following terms is not a synonym of "spread out"?
A concentrated
B dissipate
C circularise
D unfold