What is another word for total synthesis?

Synonyms for total synthesis
to·tal syn·the·sis

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total hysterectomy, total order, total parenteral nutrition, total recall, total return swap, total synthesis, totale, totaled, totaling, totalisator, totalise

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An antonym for the term "Ductile"?
A intractable
B pliable
C fictile
D malleable