What is another word for paroxysm (of extreme pain?

Synonyms for paroxysm (of extreme pain
parox·ysm (of ex·treme pain

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parotid gland, parotid vein, Parov Stelar, paroxetime, paroxysm, paroxysm (of extreme pain, paroxysmal trepidant abasia, parp, parque, parquet, parquet circle

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An antonym of "besotted"
A affluent
B stringent
C flush
D indifferent